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Numerous biological applications, from diagnostic assays to immunotherapies, rely on the use of antibody-conjugates. The efficacy of these conjugates can be significantly influenced by the site at which Immunoglobulin G (IgG) is modified. Current methods that provide control over the conjugation site, however, suffer from a number of shortfalls and often require large investments of time and.
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Sara A Galle 1 2 , Jan Berend Deijen 3 4 , Maarten V Milders 3 , Mathieu H G De Greef 5 , Erik J A Scherder 3 , Cornelia M van Duijn # 6 7 8 , Madeleine L Drent # 3 9 Affiliations 1 Department of Clinical, Neuro- and Developmental Psychology, Vrije Universiteit Amsterdam, Van Der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands. s.a.galle.
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Tom F. A. de Greef Dr. Laboratory of Macromolecular and Organic Chemistry and Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven (The Netherlands), Fax: (+31) 40-245-1036. Maarten M. J. Smulders. Laboratory of Macromolecular and Organic Chemistry and Institute for Complex Molecular.
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Maarten De Graef Ghent University | UGhent · Department of Electrical Energy, Systems and Automation Connect with experts in your field Join ResearchGate to contact this researcher and connect.
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Freek V. de Graaf, Stef A. H. Jansen, Tobias Schnitzer, E. W. Meijer, Ghislaine Vantomme. Controlling Helical Asymmetry in Supramolecular Copolymers by In Situ Chemical Modification. Journal of the American Chemical Society 2023 , 145 (26) , 14379-14386.
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Johan De Greef graduated in 2000 as a MSc in Bioscience Engineering with a major in process and environmental technology. He obtained a PhD in Chemical Engineering on the subject of flow and mass transfer in structured catalytic reactor systems.
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The rational design and implementation of synthetic, orthogonal mammalian communication systems has the potential to unravel fundamental design principles of mammalian cell communication circuits and offer a framework for engineering of designer cell consortia with potential applications in cell therapeutics and artificial tissue engineering. We lay here the foundations for the engineering of.
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Pathway complexity in supramolecular polymerization. 2012 Jan 18;481 (7382):492-6. doi: 10.1038/nature10720. Self-assembly provides an attractive route to functional organic materials, with properties and hence performance depending sensitively on the organization of the molecular building blocks. Molecular organization is a direct consequence.
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Maarten De Graef is 33-years-old, born on 19 August 1990, and is a left-footed professional football player from Belgium. Maarten De Graef is currently playing for Berlare in Division 2 Amateur as a Defender
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Antibody-based molecular recognition plays a dominant role in the life sciences ranging from applications in diagnostics and molecular imaging to targeted drug delivery and therapy. Here we report a generic approach to introduce protease sensitivity into antibody-based targeting by taking advantage of the intrinsic ability of antibodies to engage in multivalent interactions.
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A photocrosslinkable protein G variant was used as an adapter protein to covalently and site-specifically conjugate an antibody and an Fc-fusion protein to an oligonucleotide. This modular approach enables straightforward decoration of DNA nanostructures with complex native proteins while retaining their inn 2017 Emerging Investigators
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Martijn van Rosmalen 1 , Brian M G Janssen 1 , Natalie M Hendrikse 1 , Ardjan J van der Linden 1 , Pascal A Pieters 1 , Dave Wanders 1 , Tom F A de Greef 1 , Maarten Merkx 2 Affiliations 1 From the Laboratory of Chemical Biology and Institute for Complex Molecular Systems (ICMS), Department of Biomedical Engineering, Eindhoven University of.
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Martijn de Greef's 43 research works with 789 citations and 5,000 reads, including: Thermal ablation of a confluent lesion in the porcine kidney with a clinically available MR-HIFU system
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Authors Tom F A De Greef 1 , Maarten M J Smulders , Martin Wolffs , Albert P H J Schenning , Rint P Sijbesma , E W Meijer Affiliation 1 Institute for Complex Molecular Systems and Laboratory of Macromolecular and Organic Chemistry, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands. PMID: 19769364